This eBook is the premier volume of our "Mental Illness/Central Nervous System" series, focussing specifically on "PHARMACEUTICAL ISSUES IN MENTALLY ILL ADULTS & ELDERLY". This eBook release encompasses diagnoses such as controlled drugs and drug dependence, dementia, epilepsy and other seizure disorders, status epilepticus and febrile convulsions, anxiety, attention deficit hyperactivity disorder, bipolar disorder and mania, depression, inappropriate sexual behaviour, psychoses and schizophrenia, cerebral palsy and spasticity/motor neurone disease, dystonias and other involuntary movements, parkinson’s disease, nausea and labyrinth disorders, pain, chronic, analgesics, migraine, cluster headache, and other trigeminal autonomic cephalalgias, neuropathic pain, sleep disorders, and substance dependence. The content comprises a total of 1586 "MCQs with Guiding Answers" and 412 "Linked References". This eBook also contains numerous "Study Highlights or Summary Keypoints" alongside the "CLINICAL PRACTICE INSIGHTS" section. Our primary clients include medical professionals, clinical pharmacists or PharmDs, nurses, and various other individuals in the healthcare sector, such as mentors, residents, and students. We adhere to conventional design principles for all our sequential eBook publications to circumvent the trend of "hypercoloremia mania" in eBook design. This predominantly employs the official black and white colour scheme. This publication resulted from a collaborative effort with my skilled and dedicated coauthors, namely PharmDs Arwa Alashqar, Duaa Alqhaiwi, Najd Alyasjeen, Kariman Hatem, Leen Albishawi, Areej Al-Manasyeh, Marah Hussein, Eman Awwad, Farah Qaryouti, Dana AlTaweel, and Alia' Saidan. Corresponding author; Clinical Pharmacy Specialty “MOH’D NOUR” BANIYOUNES”, MSc Clinical Pharmacy, BCPS, BCCCP, BCNSP, BCACP, BCIDP