Formulating a precise hypothesis is essential for any research study, particularly those in clinical or non-clinical domain. The hypothesis offers a distinct direction for successfully accomplishing a meaningful investigation project. The aim of this book is to provide a fundamental overview of the process involved in formulating a hypothesis for a particular case study. The discussion is divided into six chapters, each structured according to the most commonly used research analysis selection method. This book serves as a guide to researchers in developing research questions and objectives tailored to their research needs. It assists students and researchers in understanding the fundamental concept and sharing the proper method for data analysis. Presented in simple language and clear approach, this book proves to be a great reference for those who are embarking on their research journey, even for beginners. Brief samples of hypothesis are also provided as a guide for new researchers. We aspire for this book to aid in the creation of robust research projects and offer valuable insights into statistical methods in applied research, among other aspects.