Computational modeling and simulation for biomedical applications have facilitated scientists and researchers in their quests to explain complex biomedical behaviors and systems virtually. It has opened-up hidden views which help researchers to make deliberate decisions in improving recent innovation while reducing the overall time, cost and materials required. Unimaginable effects and reactions caused by nature can now be represented in clearer schematics and diagrams. These versatile tools have allowed researchers to accurately conclude and predict various phenomenon prior to implementing them in real applications. Advancements in computational ability have pushed the boundaries even further. For instance, a damage mechanics of glenoid labrum can now be simulated in rocking horse phenomena (RHP) by using multiple virtual pegs even before it gets fabricated. This book showcases several successful studies that manifest the use of various computational simulation approaches in solving biomedical and bioengineering problems. It covers a wide range of topics from ankle and foot bones development to breast cancer and renal screening simulations. Each chapter focuses on a specific topic which can be understood on its own. This book will be beneficial for students, engineers, researchers as well as medical practitioners.